Colorized scanning electron micrograph of a cell (blue) infected with the Omicron strain of SARS-CoV-2 virus particles (pink), isolated from a patient sample.

The first phase of human trials studying a possible nasal COVID-19 vaccine has opened, the National Institutes of Health (NIH) announced. The clinical trial, sponsored by the federal health agency, is enrolling participants at three sites across the U.S. Researchers believe the vaccine candidate may provide even better protection against emerging variants than the COVID vaccines given via injection. “The concept is that we’re looking for next generation vaccines,” said Dr. John Brownstein, an epidemiologist and chief innovation officer at Boston Children’s Hospital and an ABC News contributor. “Throughout the pandemic, we had the incredible scientific breakthrough of COVID vaccines that happened, that got into production incredibly quickly and were safe and effective. But of course, we also recognize that there are challenges of the existing vaccines.” To read the full story.