A study recently published in the Journal of the American Medical Association determined clinical criteria for diagnosing multisystem inflammatory syndrome (MIS-C) from severe COVID-19 and Kawasaki disease, which have similar symptoms. Diagnosing and treating MIS-C – which has affected 2,600 children since May 2020 and is known to occur in children who have tested positive for SARS-CoV-2 or been exposed to someone with COVID-19 – is difficult because respiratory and gastrointestinal symptoms can be similar to severe COVID-19. Other features of MIS-C, a rare but possibly life-threatening pediatric condition that can cause severe inflammation in organs like the heart, brain, lungs, kidneys and gastrointestinal system, are very similar to Kawasaki disease, which causes inflammation in blood vessels. To read the full story.